We also discuss LIS1, Fos, SynCAM1, BDNF, Smad3, Oxytocin, and DISC1, factors that influence memory insofar as they relate to the development of memory and memory consolidation. Here, we discuss neural circuits and efferent or afferent fibers related to the hippocampus, including the entorhinal cortex to the hippocampus, hippocampus to the prefrontal cortex, and vDBChATs-dNGIs. These discoveries stimulated researchers to study the types of memories related to the neural circuits of the hippocampus. Subsequently, our understanding of the neurophysiological bases of hippocampal function was greatly enhanced by two breakthroughs: Bliss and Lomo’s finding of activity-dependent long-term potentiation (LTP) of synaptic transmission in the hippocampus, and the discovery of hippocampal place cells and neurons that encoded the spatial position of an animal reported by O’Keefe and Dostrovsky. following bilateral temporal lobe resection, the hippocampus and surrounding temporal lobe structures have been extensively studied for their role in memory. Since the description by Scoville and Milner of profound anterograde amnesia in a patient known as H.M.
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